ALPHA-CHYMO-TRYPSIN IN CATARACT EXTRACTION

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Cataract extraction with the aid of alpha-chymo-trypsin.

In all cases section was made with the von Graefe knife and one to three corneoscleral sutures were inserted. Peripheral iridectomy was performed in all except two cases where the iridectomy was complete. Alpha-chymo-trypsin (A.C.T.) 1: 5000 solution was injected through the iridectomy above and posterior to the iris below. After exactly 3 minutes the anterior chamber was irrigated with saline ...

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Crystalline Chymo-trypsin and Chymo-trypsinogen

A new crystalline protein, chymo-trypsinogen, has been isolated from acid extracts of fresh cattle pancreas. This protein is not an enzyme but is transformed by minute amounts of trypsin into an active proteolytic enzyme called chymo-trypsin. The chymo-trypsin has also been obtained in crystalline form. The chymo-trypsinogen cannot be activated by enterokinase, pepsin, inactive trypsin, or calc...

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[Intracapsular cataract extraction using alpha-chymotrypsin].

ALPHA-CHYMO-TRYPSIN (A.C.T.) is an enzyme with fibrinolytic and proteolytic properties which is prepared from bovine pancreas. It was discovered by Dr. Joaquin Barraquer in 1957 that the substance had a selective solvent action on the zonule supporting the lens. After extensive animal and postmortem experiments he applied the discovery to the living human eye with important results. He found th...

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A Method for Determining the Rennet Activity of Chymo-trypsin

The rennet activity of chymo-trypsin (or pepsin) is conveniently measured by allowing a standard solution of milk to which chymotrypsin has been added to flow slowly through a graduated pipette and observing the rate and distance of flow of the milk before it clots. The time required for chymo-trypsin to clot milk may be calculated from these observations. The rennet activity is expressed as th...

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Cataract Extraction with Alpha-chymotrypsin a Controlled Trial.

First fifty intracapsular extractions were performed in an uncontrolled series so that the operator should become thoroughly familiar with the technique. In order to make a true assessment fifty ampoules were prepared by the hospital pharmacist with their accompanying ampoule of diluent, and these were numbered 1 to 50. Some of the ampoules contained active A.C.T. and the others an inert substa...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1959

ISSN: 0007-1161

DOI: 10.1136/bjo.43.4.202